White House launches 'TrumpRx.gov' discount medication platform
The federal government is taking an active role in providing consumers access to low-cost prescription drugs.
The TrumpRx.gov website offers discounts on some of the most popular and highest-priced medications in the U.S., providing prices that a White House fact sheet says are in line with the lowest costs paid by consumers in other developed nations (known as the most-favored-nation, or MFN, price).
TrumpRx does not sell or dispense drugs, but facilitates consumer access to discounts, and then an underlying partner platform executes the pricing.
At launch, TrumpRx.gov features drugs made by the first five manufacturers to reach MFN pricing deals with the Trump Administration: AstraZeneca, Eli Lilly, EMD Serono, Novo Nordisk and Pfizer.
AstraZeneca voluntarily agreed to a range of measures President Trump requested in a letter sent to the company in July 2025 to provide U.S. consumers access to medicines at MFN prices.
[READ MORE: AstraZeneca enters discount medication agreement with Trump]
As part of the agreement, AstraZeneca will provide direct-to-consumer (DTC) sales to eligible patients with prescriptions for chronic diseases at a discount of up to 80% off list prices. The drugmaker also reached an agreement with the US Department of Commerce to delay Section 232 tariffs for three years, enabling the company to fully onshore medicines manufacturing.
Pfizer also recently agreed to participate in TrupRx.gov as part of a recently signed broader agreement with the government that will provide every state Medicaid program in the country access to MFN drug prices on Pfizer products and to offer medicines at a deep discount off the list price when selling directly to American patients.
Depending on the manufacturer of a given drug, patients with valid prescriptions will be able to access savings through coupons that can be printed or downloaded onto their phones or through channels set up by the manufacturer and integrated into TrumpRx.gov. Select examples of some of the first 40 drugs to be offered at discount via the platform include GLP-1 medications Ozempic, Wegovy and Zepbound, as well as commonly-used fertility medications and Airsupra, an inhaler used to treat asthma symptoms and attacks.
Digital discount prescriptions are a growing market
AstraZeneca is tossing its prescription bottle cap into an increasingly crowded vertical of digital retailers and platforms offering consumers online access to low-cost prescription drugs, with the added feature of being a direct-to-consumer provider.
For example, online giant Amazon offers RxPass, a $5 monthly discount prescription service for U.S. Prime members from Amazon Pharmacy initially launched in 2023, in 48 U.S. states.
And same-day pharmacy delivery from Walmart, which was initially launched to provide delivery of prescription medications in as little as 30 minutes in October 2024 and offered nationwide in January 2025, now includes refrigerated and reconstituted medications — such as insulin, GLP-1s and pediatric amoxicillin — and is available across the U.S.
Walmart also recently opened a 102,000-sq.-ft. facility in Frederick, Md. designed to fulfill up to 100,000 prescriptions a day, supporting more than 700 stores across 16 states and Washington, D.C.
Other low-cost competitors in the prescription drug marketplace include GoodRx, which began directly selling and fulfilling orders for eligible prescription and over-the-counter medications online in October 2024 and also partners with drugstore retailers including Walgreens and the pharmacy operation of Hy-Vee. In addition, GoodRx is serving as the integrated pricing source on TrumpRx for Pfizer.
In addition, billionaire entrepreneur and "Shark Tank" star Mark Cuban launched Cost Plus Drugs in 2022 as a registered pharmaceutical wholesaler, which allows it to bypass middlemen and their associated markups. Cost Plus Drugs partners with retailers including Ahold Delhaize USA.
